侧向观看 axicon 集成的微型纤维探针用于扩展焦点深度和超高侧向分辨率内镜成像
Yin Liu1, Duanhong Zhang2,3, Wenxin Li2,3
1Beijing Engineering Research Center of Industrial Spectrum Imaging, School of Automation and Electrical Engineering, University of Science and Technology Beijing, Beijing, China.
Microsystems & nanoengineering
|November 28, 2025
概括
微型光学相干断层扫描 (OCT) 内镜探头能够对狭窄的光量进行3D可视化. 这项研究引入了一种超紧的侧视OCT探头,可提高焦点深度,用于准确的诊断.
科学领域:
- 生物医学光学 生物医学光学
- 医疗成像医学成像
- 最少侵入性的技术
背景情况:
- 微型光学连贯性断层扫描 (OCT) 内镜探头对于狭窄的光度中的3D可视化至关重要,有助于早期诊断.
- 目前小型化的侧视OCT探头面临着制造限制,影响成像性能和采用.
- 直接观察技术可能会导致组织创伤,突出显示了对先进内镜解决方案的需求.
研究的目的:
- 设计和开发一个超紧的,侧视OCT光纤内镜探头,具有扩展的焦点深度 (DOF) 和高侧分辨率.
- 从理论上分析成像性能和纤维结构参数之间的关系.
- 为了证明开发的光纤探头原型的可行性和适用性.
主要方法:
- 一个全纤维复合结构的设计,用于一个超紧的侧视OCT内镜探头.
- 基于纤维结构和几何参数的成像性能的理论分析.
- 使用线性和旋转扫描方法进行实验验证.
主要成果:
- 开发一种超紧的侧视OCT光纤探头,具有扩展的DOF和高侧分辨率.
- 通过调整光纤级联结构参数,有能力灵活地定制成像性能.
- 通过扫描方法成功证明探测器的适用性和可行性.
结论:
- 设计的超紧侧视OCT纤维探测器为最小侵入性应用提供了微观的结构洞察力.
- 这项技术有可能显著提升可疑病变组织的早期和精确诊断和治疗.
- 开发的探头克服了当前技术的局限性,为在医学诊断中更广泛采用铺平了道路.
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