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Updated: Jan 10, 2026

Use of Hematopoietic Stem Cell Transplantation to Assess the Origin of Myelodysplastic Syndrome
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干细胞中染色体的可访问性揭示了髓质疏松症候群中逐渐转录的变化

Motohiko Oshima1, Naoya Takayama2, Yaeko Nakajima-Takagi1

  • 1Division of Stem Cell and Molecular Medicine, Center for Stem Cell Biology and Regenerative Medicine, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan.

Nature communications
|November 28, 2025
PubMed
概括

骨髓质疏松症候群 (MDS) 干细胞显示染色质可访问性发生变化,反映了疾病的进展和破坏正常细胞层次. 这些变化影响了髓状细胞网络激活和高血压细胞计划,有助于疾病分层.

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