相关实验视频

Updated: Jan 10, 2026

Author Spotlight: Investigating Asymmetric Cell Division Dynamics: A Protocol for Live-Imaging of Drosophila Larval Brain Explants
07:06

Author Spotlight: Investigating Asymmetric Cell Division Dynamics: A Protocol for Live-Imaging of Drosophila Larval Brain Explants

Published on: June 23, 2023

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PCM1协调中心体不对称性与极化内分体动态,以调节子细胞命运

Xiang Zhao1,2, Vincent Mouilleau3, Yiqi Wang4

  • 1Department of Bioengineering and Therapeutic Sciences, Pharmaceutical Chemistry, Programs in Biological Sciences and Quantitative Biosciences, Institute of Human Genetics, Kavli Institute for Fundamental Neuroscience, Bakar Aging Research Institute, University of California, San Francisco, California, USA. xiang.zhao@czbiohub.org.

Nature communications
|November 28, 2025
PubMed
概括

周心质物质1 (Pcm1) 通过控制放射性质原生细胞如何分裂来调节大脑发育. Pcm1通过将中心体不对称性与内体体贩运联系起来,确保适当的细胞命运,保持祖先的自我更新.

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Quantitative Immunofluorescence Assay to Measure the Variation in Protein Levels at Centrosomes09:39

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相关概念视频

Centrosome Duplication02:25

Centrosome Duplication

The primary microtubule organizing center (MTOC) in animal cells is the centrosome. A centrosome has two cylindrical centrioles at its core. Each centriole consists of nine sets of three microtubules held together by proteins. The centrioles are positioned at right angles to each other and surrounded by a shapeless protein cloud called the pericentriolar matrix, or pericentriolar material (PCM).
To ensure that each daughter cell receives a centrosome after cell division, centrosome duplication...
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The cytoplasm contains various organelles, as well as salts, proteins, and water. The distribution of...
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