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Updated: Jan 10, 2026

Overexpression and Purification of Human Cis-prenyltransferase in Escherichia coli
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Overexpression and Purification of Human Cis-prenyltransferase in Escherichia coli

Published on: August 3, 2017

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人类cis-prenyltransferase复合体中全调节的结构机制

Moshe Giladi1,2, Shiri Kredi3, Carlo Guardiani4

  • 1Department of Physiology and Pharmacology, Gray Faculty of Medical and Health Sciences, Tel-Aviv University, Tel-Aviv, Israel. moshegil@post.tau.ac.il.

Nature communications
|November 28, 2025
PubMed
概括

人类的cis-prenyltransferase (hcis-PT) 活性由Nogo-B受体 (NgBR) 通过一种全osteric机制来调节. 特定的NgBR残留物充当通信枢纽,调节酶功能并提供治疗点.

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