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Updated: Jun 19, 2026

MALDI-Mass Spectrometric Imaging for the Investigation of Metabolites in Medicago truncatula Root Nodules
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MALDI-Mass Spectrometric Imaging for the Investigation of Metabolites in Medicago truncatula Root Nodules

Published on: March 5, 2014

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一个部分,两个世界:MALDI-MSI的单细胞集成和空间转录组学在同一单个组织部分.

Tim F E Hendriks1, Gert B Eijkel1, Theodoros Visvikis1

  • 1The Maastricht MultiModal Molecular Imaging (M4I) Institute, Division of Imaging Mass Spectrometry (IMS), Maastricht University, 6229 ER, Maastricht, The Netherlands.

Scientific reports
|November 29, 2025
PubMed
概括

这项研究将质谱成像与空间转录组学相结合,用于像素级多组学分析. 工作流揭示了细胞类型内的代谢异质性,增强了对细胞功能和疾病的理解.

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相关概念视频

MALDI-TOF Mass Spectrometry01:19

MALDI-TOF Mass Spectrometry

Mass spectrometry is a powerful characterization technique that can identify and separate a wide variety of compounds ranging from chemical to biological entities, based on their mass-to-charge ratio (m/z). The instruments that allow this detection, known as mass spectrometers, have three components: an ion source, a mass analyzer, and a detector. These spectrometers differ based on the nature of their ion source and analyzers.Matrix-assisted laser desorption ionization (MALDI) is a commonly...