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试验的适应性设计,旨在优化实施策略和额外的中间分析的影响:模拟研究

Erin Nolan1,2,3, Daniel Barker4,5, Elizabeth Holliday4

  • 1School of Medicine and Public Health, The University of Newcastle, Callaghan, NSW, Australia. Erin.Nolan@hmri.org.au.

BMC medical research methodology
|November 29, 2025
PubMed
概括

与固定设计相比,用于实施试验的适应性设计可以提高效率和功率. 这些适应性方法可以减少浪费的资源,允许根据临时分析提前停止或放下手臂.

关键词:
适应性设计 适应性设计贝叶斯语 贝叶斯语 贝叶斯语 贝叶斯语实施 实施 实施优化 优化 优化试验设计试验设计.

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