左束支部区域节奏对心脏重塑和功能的影响:倾向得分与右心室节奏相匹配
Shigeng Zhang1, Zongbin Li2, Junfang Guo1
1Department of Cardiology, The Affiliated People's Hospital of Jiangsu University, 8 # Dianli Road, Zhenjiang, 212002, China.
BMC cardiovascular disorders
|November 29, 2025
概括
与传统的右心室节奏 (RVP) 相比,左捆支部区域节奏 (LBBAP) 改善了心脏功能和心房阻塞患者的重塑. 对于需要显著的心室节奏的患者,LBBAP可能是一个优越的节奏策略.
科学领域:
- 心脏病学 心脏病学
- 电子生理学 电子生理学
- 心脏节拍是因为心脏节拍.
背景情况:
- 传统的右心室节奏 (RVP) 可以导致心脏失调,节奏诱导的心肌病 (PICM),心力衰竭和死亡率增加.
- 左捆分支区域节奏 (LBBAP) 提供了一种更生理化的节奏方法.
研究的目的:
- 为了比较LBBAP与RVP对心脏功能和心房阻塞 (AVB) 患者心脏功能重塑的影响.
主要方法:
- 分析了118名接受LBBAP的AVB患者.
- 倾向性得分匹配创建了一个1:1队列,由41名接受LBBAP和41名接受RVP的患者组成.
- 心声学参数和NYHA分类在1年后期进行评估.
主要成果:
- LBBAP维持或改善左心室喷射率 (LVEF),而RVP显示下降趋势.
- 与RVP相比,LBBAP显著改善了NYHA分类.
- 与RVP相比,LBBAP显示了降低PICM的趋势 (0%与9.8%相比).
结论:
- 在患有高心室节奏负担的患者中,LBBAP可能是改善心脏重塑和功能的首选节奏策略.
- 在管理AVB患者方面,LBBAP比传统RVP提供了潜在的优势.
相关概念视频
Factors Influencing Heart Rate
The heart rate, or pulse rate, is a vital indicator of cardiovascular health. It reflects the number of times the heart beats per minute. Various physiological and environmental factors influence heart rate, increasing or decreasing cardiac output. Understanding these factors is crucial for assessing heart function and identifying potential health issues.
Let us explore the significant factors affecting heart rate, including age, body temperature, posture, acute pain, chemical influences,...
Let us explore the significant factors affecting heart rate, including age, body temperature, posture, acute pain, chemical influences,...
Pathophysiology of Cardiac Performance
Typical heart performance is influenced by heart rate, rhythm, myocardial contraction, and metabolism or blood flow. The cardiac muscle exhibits distinct electrophysiological features, including pacemaker activity and calcium channel control, which play a vital role in the heart's response to various drugs. The autonomic nervous system, comprising the sympathetic and parasympathetic branches, regulates heart rate. Sympathetic activation increases heart rate, while parasympathetic activation...
Heart Valves
The human heart is a complex organ with an intricate system of valves that regulate blood flow. There are two main types of valves: atrioventricular (AV) valves and semilunar valves.
The AV valves prevent the backflow of blood from the ventricles to the atria during ventricular contraction. These valves function with the assistance of the chordae tendineae and papillary muscles. When the ventricles are relaxed, the chordae tendineae are slack, allowing blood to flow from the atria into the...
The AV valves prevent the backflow of blood from the ventricles to the atria during ventricular contraction. These valves function with the assistance of the chordae tendineae and papillary muscles. When the ventricles are relaxed, the chordae tendineae are slack, allowing blood to flow from the atria into the...
Imbalances in Cardiac Output
The heart's primary function is to pump blood throughout the body, maintaining a balance between blood sent out (cardiac output) and blood returning (venous return). If this balance is disrupted, it can result in congestive heart failure (CHF), a severe condition where the heart becomes an inefficient pump, leading to inadequate blood circulation.
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to send blood...
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to send blood...
Mitral Regurgitation I: Introduction
Mitral regurgitation is characterized by the backward circulation of blood from the left ventricle to the left atrium during systole, a phase of the cardiac cycle when the heart contracts and pumps blood out of the chambers. This abnormal flow occurs primarily due to the dysfunction of the mitral valve or its supporting structures, which include the mitral leaflets, chordae tendineae, annulus, and papillary muscles.Etiology and Mechanisms:Primary Mitral Regurgitation: This type arises from...
Mitral Stenosis I: Introduction
Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...


