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血压变化及其在急性疾病和危急疾病中的有用性:系统性审查
1Department of Emergency Medicine, ShengJing Hospital of China Medical University, 36 Sanhao St, Shenyang, Liaoning, 110004, China.
BMC anesthesiology
|November 29, 2025
概括
血压变化 (BPV) 与急性和危急疾病中的非死亡结果有关. 需要进一步的研究来验证BPV作为紧急和重症监护机构的预测工具.
科学领域:
- 关键护理医学 关键护理医学
- 心血管生理学心血管生理学
- 自主神经系统功能 自主神经系统功能
背景情况:
- 血压变化 (BPV) 是自主神经系统 (ANS) 功能的标志物.
- 了解BPV与患者结果之间的关系在急性和危急疾病中至关重要.
- 为了研究这种关系,进行了系统审查和元分析.
研究的目的:
- 为了评估血压变化 (BPV) 与急性疾病和危急疾病患者的结果之间的关联.
- 通过系统性审查和元分析,综合现有研究的证据.
- 探索BPV作为紧急和重症监护中的预测工具的潜力.
主要方法:
- 在PubMed和谷歌学者数据库的系统文献搜索.
- 包括13项研究,包括21,475名参与者进行元分析.
- 使用纽卡斯尔-太华尺度和AHRQ方法指南进行偏差风险评估.
- 针对异质性的子组和敏感性分析.
主要成果:
- 血压值增加1个单位与非死亡结果的适度增加有关 (OR 1.06).
- 特定的BPV指标,如静脉血压变化标准偏差 (SBPV SD),与非死亡结果有显著的相关性.
- 在严重感染 (OR 1.09) 和中风队列 (OR 1.05) 中,SBPV SD 显示出更强的关联.
结论:
- 在急性和危急疾病中,BPV和非死亡结果之间存在温和的相关性.
- BPV指标,特别是SBPV SD,显示出潜在的预测工具,用于特定的条件,如中风和严重的感染.
- 需要进一步的研究来验证BPV的预测效用,并在临床环境中探索治疗调制.
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