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通过内4D流MRI进行血液动力学测量的重复性和可重复性:一个多供应商和多软件交叉比较研究

Mingfang Luo¹, Lini Liu¹, Rui Li²

¹Department of Radiology, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, No. 32, Section 2, 1st Ring Road (West), Chengdu, 610072, China.

BMC medical imaging

|November 29, 2025

概括

供应商的协议显示,内四维流量MRI (4D Flow MR) 的流速差异很小. 然而,后处理软件对结果产生重大影响,需要单平台使用或对多中心研究进行校准.

科学领域:

医疗成像医学成像
心血管研究研究心血管研究
神经成像是一种神经成像.

背景情况:

现有多种协议和软件用于内4D流MR数据采集和血液动力学参数计算.
有限的验证数据量化了各种供应商和软件平台之间的测量差异.
本研究解决了对定量结果进行全面交叉比较分析的需求.

研究的目的:

从内4D流MR数据中获得的定量血液动力学参数进行全面的交叉比较分析.
为了评估三个主要的MRI供应商和三个后处理软件平台的测量差异.
为了评估血液动力学参数提取的观察者内部和观察者之间的一致性.

主要方法:

在20名健康志愿者身上,使用3种不同的3.0TMRI扫描仪进行了内4D流式MRI成像.
使用CVI42,MASS和TS FLOW后处理软件分析了每个受试者的9个主要内动脉 (共180个).
包括流量,Vmax,Vavg和容器面积在内的血液动力学参数被提取并通过供应商和软件进行比较.

主要成果:

在扫描仪之间没有发现显著的流速差异 (p > 0.05),表明可互换使用.
流速和Vmax显示MASS和CVI42之间的等价性;Vavg在TS FLOW和CVI42之间的等价性.
船舶区域协议在软件上有很大的差异 (ICC = 0.083-0.577);TS FLOW显示出高的重复性和可重复性.

结论:

供应商扫描协议的流速变化比其他后处理软件少.
一致的多中心临床研究需要使用单个后处理软件平台或实施软件校准.
仔细考虑软件选择对于在内4D流MR中准确和可重复的血液动力学评估至关重要.

关键词:

4D 流动流动 4D 流动血液动力学血液动力学内动脉内动脉内动脉阶段对比磁共振成像成像技术

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