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在非创伤性大出血中进行医院前输血:一项追溯观察性研究

Harsha Kodakadath¹, Seán Dillane², Jo Griggs^2,3

¹Air Ambulance Charity Kent Surrey Sussex, Hanger 10, Redhill Aerodrome, Redhill, Surrey, RH1 5YP, UK. kharshaaravind@gmail.com.

Scandinavian journal of trauma, resuscitation and emergency medicine

|November 29, 2025

概括

对于非创伤性出血的医院前输血显著改善了患者的生理学. 这表明,早期血液成分的使用可能有利于经历重大非创伤性出血的患者.

科学领域:

紧急医疗紧急医疗
创伤外科手术创伤外科
关键的护理关键的护理

背景情况:

对于创伤性出血,已经建立了医院前输血协议.
对于非创伤性大出血管理,仅有有限的指导.
对历史数据的分析是必要的,以告知输血实践.

研究的目的:

描述非创伤性大出血的发生率.
为了分析当前的医院前血液产品的管理,对非创伤性出血进行分析.
评估医院前输血对患者生理学的影响.

主要方法:

追溯观察队列研究.
使用来自空中救护车慈善机构肯特郡苏里郡和萨塞克斯州 (2013-2024) 的患者数据.
包括接受非创伤性大出血的医院前血液组件的患者,分析人口统计学,出血原因,生理学和输血细节.

主要成果:

确定了50名患有非创伤性重大出血的患者 (平均年龄为48岁).
胃肠道出血是最常见的原因 (n=21).
输血是由79mmHg的平均静缩血压触发的,有显著的生理改善 (冲击指数1.39到0.97,p<0.001).

结论:

医院前输血显然改善了非创伤性出血患者的生理参数.
这些发现支持了早期血液成分的潜在益处在这个患者群体中.
对非创伤性出血的优化输血策略的进一步研究是有必要的.

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