针对泛性焦虑症的有效性:一个系统的审查
Jingling Lai1, Yikun Wang2, Xiaoyan Yao1
1Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Annals of general psychiatry
|November 29, 2025
概括
针,单独或与药物一起,有效地减少了与药物或假针相比的泛性焦虑障碍 (GAD) 症状. 虽然有希望,但由于证据确定性较低,需要进一步进行高质量的试验.
科学领域:
- 综合医学是一个整体的医学.
- 麻醉学 麻醉学
- 精神病学是一个精神病学.
背景情况:
- 通用焦虑症 (GAD) 是一种普遍存在的心理健康状况.
- 目前的治疗方法包括药物治疗和心理治疗,但疗效和副作用各不相同.
- 针是一种潜在的补充或替代性治疗GAD.
研究的目的:
- 系统地审查和分析针治疗GAD的疗效和安全性.
- 为了比较单独的针和与药物联合的针,对抗药物或假针.
- 为了确定GAD治疗的最佳针参数.
主要方法:
- 在多个数据库 (PubMed,Embase,CENTRAL等) 进行全面的文献搜索. 在2025年8月之前.
- 包括随机对照试验 (RCT) 进行严格的质量评估 (RoB 2.0) 和证据确定性评估 (GRADE).
- 使用RevMan 5.3进行的元分析,根据对比器和针参数进行子组分析.
主要成果:
- 与单独服用药物相比,针 (单独或与药物结合) 显著降低了汉密尔顿焦虑评分表 (HAMA) 的得分.
- 针在减少焦虑症状方面表现出优于假针的优势.
- 在总有效率,SAS得分和CGI-EI中观察到改善的结果,针组中不良事件发生率较低.
结论:
- 针作为单一疗法或辅助疗法,与药物治疗或假针相比,对GAD显示出更高的疗效和安全性.
- 最佳的治疗持续时间似乎是4-6周,具体频率因单疗法和联合疗法而异.
- 尽管结果很有希望,但证据的确定性低至非常低,需要进一步进行高质量的RCT.
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