相关实验视频

Updated: Jan 10, 2026

An In Vitro Batch-culture Model to Estimate the Effects of Interventional Regimens on Human Fecal Microbiota

An In Vitro Batch-culture Model to Estimate the Effects of Interventional Regimens on Human Fecal Microbiota

Published on: July 31, 2019

肠道微生物调节作为血糖调节的前体通过Moringa Oleifera 叶子水性提取物-一个实验研究实验研究

Aamina Sabir¹, Shaista Jabeen¹, Hafsa Kamran¹

¹University Institute of Diet and Nutritional Sciences, Faculty of Allied Health Sciences, The University of Lahore, Lahore, Pakistan.

Molecular nutrition & food research

|November 29, 2025

概括

莫林加叶 (MO) 提取物显示出显著的益生菌作用,促进了老鼠的乳酸菌生长. 该研究还发现MO具有抗高血糖特性,在糖尿病模型中有效降低血糖水平.

科学领域:

药理学和传统医学的医学.
微生物学和肠道健康
生物化学和代谢障碍生物化学和代谢障碍

背景情况:

Moringa oleifera (MO),被称为鼓杆,以其药用特性而闻名.
植物作为益生菌的潜力及其对葡萄糖代谢的影响需要科学研究.
糖尿病是一种日益严重的全球健康问题,需要新的治疗策略.

研究的目的:

为了研究Moringa oleifera叶子提取物的益生菌活性.
为了评估Moringa oleifera在糖尿病老鼠模型中的葡萄糖平衡潜力.
为了确定观察到的效果的最佳剂量.

主要方法:

实验研究涉及24只雄性白化老鼠,诱导与链毒素-糖尿病.
鼠被分为四组:对照组 (甲胺) 和三组治疗组,接受100,200和300毫克/公斤/天的MO叶子提取物.
在21天的时间里,便分析乳酸菌数量和血糖水平监测.

主要成果:

便分析显示,MO治疗组与对照组 (10^3 CFU) 相比,MO治疗组的Lactobacillus数量增加 (10^4-10^5 CFU).
抗高血糖作用在100毫克/公斤/天剂量时最为明显,显著降低血糖从152.50±7.7至119±7.07 (p=0.010).
较高剂量的MO提取物显示出较少显著的抗高血糖效应 (p>0.05).

结论:

莫林加橄 (Moringa oleifera) 呈现出有希望的益生菌性质,由增强的乳杆菌增殖证明.
这种植物具有显著的抗高血糖潜力,特别是在100毫克/公斤/天的剂量下.
建议进行进一步的长期研究,以确定Moringa oleifera的最终有效剂量和作用机制.

更多相关视频

Investigating the Alleviating Effects of Bacillus cereus Administration on Colitis through Gut Microbiota Modulation

Investigating the Alleviating Effects of Bacillus cereus Administration on Colitis through Gut Microbiota Modulation

Published on: July 27, 2022

Murine Fecal Isolation and Microbiota Transplantation

Murine Fecal Isolation and Microbiota Transplantation

Published on: May 26, 2023

相关概念视频

Hormones Regulating Blood Glucose

Hormones Regulating Blood Glucose

Insulin is released by beta cells of the pancreas when blood glucose levels are high. It facilitates glucose absorption and utilization in insulin-dependent cells with insulin receptors on their plasma membranes. Insulin promotes glucose uptake by increasing the number of glucose transport proteins in the cell membrane, allowing glucose to enter the cell. As a result, glucose utilization and ATP production are enhanced.
In addition to accelerating glucose uptake and utilization, insulin has...

Oral Hypoglycemic Agents: α-Glucosidase Inhibitors

Oral Hypoglycemic Agents: α-Glucosidase Inhibitors

α-glucosidase inhibitors, including acarbose (Precose), miglitol (Glyset), and voglibose (Voglib) (primarily available in Asia), are drugs that control blood sugar levels by delaying the digestion of starch and disaccharides. They achieve this by inhibiting α-glucosidase enzymes in the intestine, which slow the absorption of carbohydrates in the intestine, which in turn leads to a prolonged release of the glucoregulatory hormone GLP-1 from intestinal L-cells.
Acarbose and miglitol are...

Overview of Metabolism

Overview of Metabolism

Living cells constantly carry out various chemical reactions which are necessary for their proper functioning. These reactions are interlinked to one another via multiple pathways. The collection of these chemical reactions is known as metabolism.
Plant Metabolism
Sunlight, the primary source of energy in plants, is first absorbed by the chlorophyll pigments present in their leaves. Plants then use this energy to carry out photosynthesis, where water is oxidized into oxygen and carbon dioxide...