相关实验视频

Updated: Jun 25, 2026

Procedure for Human Saphenous Veins Ex Vivo Perfusion and External Reinforcement

Procedure for Human Saphenous Veins Ex Vivo Perfusion and External Reinforcement

Published on: October 1, 2014

静脉封闭的非热HIFU治疗:来自临床前动物研究的组织学证据

Olivier Pichot¹, Alice Ganeau², Pierre Combes³

¹Department of Vascular Medicine, Groupement Hospitalier Mutualiste, Grenoble, France.

|November 29, 2025

概括

非热高强度聚焦超声波 (NT-HIFU) 通过化成功诱导羊的静脉封闭. 组织学分析显示了显著的亲密破坏和介质纤维化,适当的超声波时间将副作用降到最低.

科学领域:

血管外科血管外科
医学超声波医学超声波
临床前研究临床前研究

背景情况:

内静脉化是一种新兴的静脉治疗技术.
了解非热高强度聚焦超声波 (NT-HIFU) 对静脉的体内影响对于临床转化至关重要.

研究的目的:

通过使用NT-HIFU对绵羊静脉进行内静脉内腔的体内效应的研究.
进行组织学分析,以评估静脉壁损伤和流膜消灭.

主要方法:

超声导向的NT-HIFU被用于诱导绵羊侧静脉 (LSVs) 的腔化.
在四个LSV中测试了不同的超声波持续时间 (30秒,20秒,10秒).
进行了临床,超声波和组织学后续检查,以评估静脉封闭和组织反应.

主要成果:

在所有接受治疗的LSV中,双重超声波证实了静脉消灭.
组织学分析显示,在93.8%的病例中,LSV完全或部分消失.
观察到显著的亲密破坏和介质纤维化,随着不同程度的偶然参与和免疫透.

结论:

使用NT-HIFU的内静脉腔化在临床前的绵羊模型中有效导致静脉封闭.
该程序导致显著的组织学变化,包括内脏破坏和介质纤维化.
优化超声波时间至关重要,以避免皮肤损伤和周周静脉组织重塑等不良影响.

关键词:

动物研究动物研究洞化洞化洞化组织学组织学非热的高强度聚焦超声波.

更多相关视频

An Ultrasonic Tool for Nerve Conduction Block in Diabetic Rat Models

An Ultrasonic Tool for Nerve Conduction Block in Diabetic Rat Models

Published on: October 20, 2017

Deep Vein Thrombosis Induced by Stasis in Mice Monitored by High Frequency Ultrasonography

Deep Vein Thrombosis Induced by Stasis in Mice Monitored by High Frequency Ultrasonography

Published on: April 13, 2018

相关概念视频

Varicose Veins II: Diagnostic Studies and Interprofessional Care

Varicose Veins II: Diagnostic Studies and Interprofessional Care

Varicose veins, or varicosities, develop when the valves in the veins, which control blood flow, weaken or damage. It causes blood to pool and the veins to enlarge. Understanding the clinical manifestations, diagnostic approaches, and management options for varicose veins is crucial for effective treatment and relief.Clinical manifestationsClinical manifestations of varicose veins include a heavy, achy feeling or pain after prolonged standing or sitting. This discomfort can often be relieved by...