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Pulmonary Hypertension: Classification and Pathogenesis01:30

Pulmonary Hypertension: Classification and Pathogenesis

533
Pulmonary hypertension (PH) is a severe health condition in which the mean pulmonary arterial pressure increases to 25 mmHg or more, even when the body is at rest. This high pressure in the blood vessels that transport blood from the heart to the lungs can cause various symptoms, including shortness of breath, can lead to right heart failure, and significantly affect the overall quality of life.
There are various classifications for PH, each relating to different underlying causes and also...
533
Adrenal Gland Disorders01:27

Adrenal Gland Disorders

2.8K
Adrenal gland disorders manifest when the production of adrenal hormones deviates from the norm, resulting in either excessive or insufficient concentrations.
Adrenal insufficiency, characterized by insufficient cortisol and aldosterone production, leads to conditions like Addison's disease. This disorder, affecting the adrenal cortex, exhibits symptoms such as skin bronzing, dehydration, low blood pressure, fatigue, and weight loss. Congenital adrenal hyperplasia, a genetic ailment causing...
2.8K
Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

879
Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
879
Primary Lymphoid Organs01:16

Primary Lymphoid Organs

14.5K
Primary lymphoid organs are pivotal in the formation, development, and maturation of lymphocytes, the white blood cells that serve as the backbone of our immune system. This crucial function underscores their fundamental role in maintaining our overall health and immunity. The two primary lymphoid organs of prime importance are the red bone marrow and the thymus.
The red bone marrow is a soft, spongy tissue nestled in the interior of long bones such as the humerus and femur. It is the site...
14.5K
The Pituitary Gland01:17

The Pituitary Gland

9.7K
The pituitary is a small endocrine organ in the sphenoid bone under the hypothalamus. Primarily, the pituitary in adults has two distinct anatomical and functional regions— the anterior and posterior lobes. During human fetal development, a third pituitary gland region called the pars intermedia atrophies and disappears. However, some of its cells migrate and exist adjacent to the anterior pituitary in adults.
9.7K
Hormones of the Pituitary Gland01:27

Hormones of the Pituitary Gland

9.2K
The small, pea-sized pituitary gland is located at the base of the brain. It is crucial in regulating various bodily functions, from growth to reproduction. The gland is divided into the anterior lobe and the posterior lobe. The secretory cell clusters in the pars distalis of the anterior pituitary lobe are controlled by hypothalamic regulators and synthesize six primary hormones.
The most abundantly secreted hormone from the anterior lobe is the growth hormone, which controls overall growth by...
9.2K

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相关实验视频

Updated: Jan 6, 2026

Induction of Experimental Autoimmune Hypophysitis in SJL Mice
10:38

Induction of Experimental Autoimmune Hypophysitis in SJL Mice

Published on: December 17, 2010

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主要的低性炎:分类审查

Christie G Turin1, B K Kleinschmidt-DeMasters2

  • 1Division of Endocrinology, Metabolism and Diabetes, Department of Medicine, University of Colorado, Aurora, CO, USA.

Journal of neuropathology and experimental neurology
|November 29, 2025
PubMed
概括
此摘要是机器生成的。

初级下垂体炎是一种炎症性垂体状况,具有诊断方面的挑战. 组织学分类有所不同,但类固醇治疗,有时与rituximab一起,在所有类型中都是有效的,可能会减少对精确诊断的需求.

关键词:
在IgG4的基础上,IgG4与IgG4相关的疾病带有多阳性炎的颗粒瘤症.它是颗粒状的,有颗粒的.低血压症是什么意思?这是一种淋巴细胞性淋巴细胞.血清阴性 血清阴性

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Preparation of Mouse Pituitary Immunogen for the Induction of Experimental Autoimmune Hypophysitis
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Preparation of Mouse Pituitary Immunogen for the Induction of Experimental Autoimmune Hypophysitis

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Author Spotlight: A Focus on Standardized Salivary Gland Ultrasound Protocol in Connective Tissue Disease Research
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相关实验视频

Last Updated: Jan 6, 2026

Induction of Experimental Autoimmune Hypophysitis in SJL Mice
10:38

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Published on: December 17, 2010

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Preparation of Mouse Pituitary Immunogen for the Induction of Experimental Autoimmune Hypophysitis
10:52

Preparation of Mouse Pituitary Immunogen for the Induction of Experimental Autoimmune Hypophysitis

Published on: December 17, 2010

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Author Spotlight: A Focus on Standardized Salivary Gland Ultrasound Protocol in Connective Tissue Disease Research
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Author Spotlight: A Focus on Standardized Salivary Gland Ultrasound Protocol in Connective Tissue Disease Research

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科学领域:

  • 内分泌学 在内分泌学.
  • 病理学 病理学 病理学
  • 免疫学 免疫学 免疫学

背景情况:

  • 主要的低血位炎被分为淋巴细胞性,粒状,死性或IgG4相关的疾病.
  • 二次性低体位炎与全身性疾病有关,往往否定了活检的需要.
  • 主要的低血位炎可以模仿垂体瘤,需要组织学确认.

研究的目的:

  • 详细介绍原发性低血清炎病例,并讨论组织学分类中的挑战.
  • 探索IgG4+细胞在不同类型的低血炎亚型中的作用.
  • 为了评估治疗结果,而不考虑精确的组织学诊断.

主要方法:

  • 一系列的病例包括四名患有初级低体质炎的妇女.
  • pituitary活检的组织病理学分析,包括IgG4染色.
  • 对临床表现,疑似诊断和治疗反应的审查.

主要成果:

  • 四名女性 (32-76岁) 出现了虚弱和视觉变化等症状,怀疑患有垂体宏腺瘤.
  • 活检显示了淋巴细胞低性炎 (有/没有IgG4+细胞) 和粒状低性炎 (有亡,IgG4+细胞,巨细胞).
  • 使用类固醇治疗,在一个案例中使用Rituximab,在不同的组织类型中显示出有效性.

结论:

  • 原发性低血位炎的组织学分类可能具有挑战性,具有IgG4+细胞等特征的重叠.
  • 颗粒状和死类型不太常见,并且可以具有众多的IgG4+细胞.
  • 使用类固醇和潜在的rituximab的治疗可能对所有类型的低血清炎有效,可能会减少对精确组织学区分的依赖.