简短的精神动力学-人际交往治疗对于有自我伤害史的成年人:SafePIT RCT
Elspeth Guthrie1, Bethan Copsey2, Alexandra Wright-Hughes2
1Leeds Institute of Health Sciences, University of Leeds, Leeds, UK.
Health technology assessment (Winchester, England)
|November 29, 2025
概括
该试验调查了自我伤害的精神动态交际疗法,由于招募率低,该试验提前关闭. 虽然没有统计数据,但初步数据表明潜在的好处,为未来的自我伤害干预研究提供信息.
科学领域:
- 精神病学和心理健康 精神病学和心理健康
- 临床心理学 临床心理学
- 卫生经济学 卫生经济学
背景情况:
- 自伤导致英国每年超过20万次住院,耗资1.33亿至1.62亿英.
- 系统审查表明,心理干预可以减少痛苦和自我伤害的重复.
研究的目的:
- 评估心理动力学-人际关系治疗加上标准护理的有效性和成本效益,以及对那些自我伤害的个人单独的标准护理.
- 评估干预对自我伤害重复,心理困扰,焦虑,绝望,人际功能和生活质量的影响.
主要方法:
- 一个务实的,多中心的,个别随机对照试验与内部试点.
- 18岁以上因自我伤害而入院的参与者被随机分配到接受简短的精神动态交际治疗或标准护理.
- 主要结局是自我伤害重复导致住院的时间;次要结局在6个月和12个月后进行评估.
主要成果:
- 该试验因招聘挑战而提前结束,共有22名参与者,主要受到COVID-19大流行影响.
- 对6个月随访数据的初步分析显示,干预组中出现了两例自我伤害重复,对照组中没有.
- 经济调查结果显示,生活质量或资源使用没有显著变化,干预成本对现实世界实施假设敏感.
结论:
- 该试验无法招募计划中的样本大小,阻止了关于有效性和成本效益的最终结论.
- 尽管早期关闭,这项研究提供了有价值的见解,挑战的招聘在一场大流行期间的自我伤害干预措施.
- 为未来的试验设计和交付提供建议,以提高类似干预的招聘和成功率.
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