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大脑侧腔室不对称:体积MRI研究的元分析和元回归

Ronen Spierer¹, David Shaked Zari², Shai Shrot³

¹Technion - Israel Institute of Technology, Haifa, Israel. rospierer@gmail.com.

|November 29, 2025

概括

这项元分析发现,在健康个体中,左侧心室平均比右侧心室大6.5%. 这种一致的不对称性是理解大脑结构和神经疾病的重要发现.

科学领域:

神经成像是一种神经成像.
放射学放射学是一门学科.
人类解剖学人类解剖学

背景情况:

侧心室通常是对称的,在磁共振成像 (MRI) 中作为参考.
侧腔室之间的体积不对称是一个常见的放射学观察.

研究的目的:

在健康个体中,系统地评估一侧心室是否平均比另一侧心室大.
为了研究心室不对称的潜在调节者.

主要方法:

在三个数据库中进行系统的文献搜索,对健康受试者的MRI报告侧腔室体积的研究进行了系统的文献搜索.
对58项研究 (8,642名受试者) 的元分析和元回归以探索不对称性的调节者.

主要成果:

在几乎所有纳入的研究中都发现了显著的不对称性.
在58项研究中,左侧心室在47项研究中大于右侧心室.
左侧心室平均比右侧心室大6.5% (p < 0.0001);不对称性与心室总体积相关,但不与年龄或性别相关.

结论:

证实左侧心室通常比右侧心室大.
强调了解健康的不对称边界的重要性,因为它与神经和精神疾病的联系.
建议未来的研究来澄清异质性的来源,以改善临床应用.

关键词:

大脑的不对称性侧心室是侧心室的一个部分.横向性横向性横向性这就是为什么MRI是MRI.神经解剖学是一个神经解剖学.

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