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主要的ncRNA-mRNA网络由Polyascus sp.进行调节. 感染:对Eriocheir sinensis中的眼茎进行比较性转录基因分析

Jing Xie¹, Congping Ying², Zhen Tang²

¹Key Laboratory of Freshwater Fisheries and Germplasm Resources Utilization, Ministry of Agriculture and Rural Affairs, Freshwater Fisheries Research Center, Chinese Academy of Fishery Sciences, Wuxi, Jiangsu, China; Wuxi Fisheries College, Nanjing Agricultural University, Wuxi, Jiangsu, China.

Comparative biochemistry and physiology. Part D, Genomics & proteomics

|November 29, 2025

概括

这项研究揭示了涉及中国手套的长非编码RNA (lncRNAs).

科学领域:

海洋生物学海洋生物学
基因组学就是基因组学.
寄生虫学的寄生虫学

背景情况:

中国 (Eriocheir sinensis) 是一个商业上重要的水产养殖物种.
寄生于Polyascus sp.的寄生虫行为 (奴) 对的生长和发育产生负面影响.
了解宿主-寄生虫分子相互作用对于水产养殖管理至关重要.

研究的目的:

在中国小中识别新型长非编码RNA (lncRNAs).
研究 lncRNAs 在宿主对 Polyascus sp. 的反应中的作用. 寄生主义. 寄生主义.
阐明寄生虫的lncRNA介导调节的分子机制.

主要方法:

来自寄生和非寄生的眼组织的比较转录组测序.
对 lncRNAs 的识别和差异表达分析.
对目标mRNA的基因组丰富分析 (GSEA) 和 lncRNA-mRNA相互作用网络的构建.

主要成果:

发现了2746个新的lncRNAs,其中735个在男性和394个在女性中差异地表达.
在男性中,lncRNAs显著调节与皮层结构,氨基酸代谢和基代谢相关的途径.
lncRNAs调节小分子代谢过程和女性的氧化还原酶活性.

结论:

lncRNAs在中国小对Polyascus sp.的生理反应中起着至关重要的作用. 寄生主义. 寄生主义.
这项研究为类动物的lncRNA介导基因调节提供了新的见解.
这些发现有助于理解宿主-寄生虫相互作用和潜在的水产养殖应用.

关键词:

这里是Eriocheir sinensis的原点.化化化寄生主义是一种寄生主义.波利亚斯库斯 (Polyascus sp.) 是一个有趣的植物.这就是mRNA-lncRNA.

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lncRNA - Long Non-coding RNAs

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In humans, more than 80% of the genome gets transcribed. However, only around 2% of the genome codes for proteins. The remaining part produces non-coding RNAs which includes ribosomal RNAs, transfer RNAs, telomerase RNAs, and regulatory RNAs, among other types. A large number of regulatory non-coding RNAs have been classified into two groups depending upon their length – small non-coding RNAs, such as microRNA, which are less than 200 nucleotides in length, and long non-coding RNA...

lncRNA - Long Non-coding RNAs

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Leaky Scanning

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