在外科手术期间使用大麻来缓解手术后疼痛,在立即的全塑性乳房重建中使用大麻
Nancy Qin1, Lucy Wei1, Carson Gundlach1
1Weill Cornell Medical College, New York, NY, USA.
Journal of plastic, reconstructive & aesthetic surgery : JPRAS
|November 29, 2025
概括
接受乳腺切除重建的患者使用大麻与术后疼痛和阿片类药物消费增加有关. 然而,在调整其他因素后,这种关联并不显著,这表明需要个性化疼痛管理.
科学领域:
- 在瘤学瘤学.
- 疼痛管理 疼痛管理
- 整形外科 整形外科 整形外科
背景情况:
- 由于美国正在发展的合法化,大麻使用量增加.
- 需要了解大麻对手术恢复的影响.
- 专注于乳房切除和全塑性重建患者.
研究的目的:
- 评估大麻使用对术后疼痛的影响.
- 评估乳腺切除和重建后对阿片类药物消费的影响.
- 确定大麻使用是否影响疼痛评分和阿片类药物需求.
主要方法:
- 经过立即双边组织扩展器 (TE) 重建的乳房切除术 (2021-2025) 患者的回顾性审查.
- 被归类为大麻使用者或非使用者的患者.
- 分析了术后疼痛评分,阿片类药物消费,排放量和补充率.
主要成果:
- 在未经调整的分析中,大麻使用者 (n=40) 与非使用者 (n=197) 相比,报告的疼痛评分和阿片类药物使用率显著更高.
- 大麻使用者在0-12h,12-24h和整体上表现出更高的疼痛.
- 大麻使用者在24小时内和累积地观察到更高的阿片类药物消费 (MME);补充请求也更频繁.
- 多变量回归表明,大麻使用不是阿片类药物使用的独立预测因素,但显示了增加补充请求的趋势.
结论:
- 在未调整的模型中,大麻使用与术后疼痛和阿片类药物需求增加有关.
- 在调整了混因素后,大麻使用并不是阿片类药物消费的独立预测因素.
- 大麻使用可能表明对止痛药的需求更高,支持量身定制的术后疼痛策略.
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