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微流体工程的三重响应氨酸交叉连接的微凝,用于轻度氧化还原触发化学疗法

Marcin Mackiewicz1, Malgorzata Palusinska2, Tomasz S Kaminski1

  • 1Department of Molecular Biology, Institute of Biochemistry, Faculty of Biology, University of Warsaw, Miecznikowa 1, 02-096, Warsaw, Poland.

Biomaterials advances
|November 29, 2025
PubMed
概括

使用N,N'-二烯-L-二盐 (DACS) 的新型氧化还原敏感微凝,可为向化疗提供高效,单步的多克索鲁比辛封装. 这些对刺激有反应的药物载体在瘤条件下表现出增强的释放和选择性癌细胞毒性.

关键词:
氨酸交叉连接的微凝.多克索鲁比封装封装的方法谷氨触发释放的诱导作用微流体合成 微流体合成单分散的水凝颗粒降氧反应药物递送过程中的药物递送.三重刺激反应的微凝.

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