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自组装的聚合物纳米粒子用于氧化还原和基因调节的骨关节炎治疗

Bing Wu1, Ye Yang2, Xiancheng Huang1

  • 1Department of Sports Medicine and Rehabilitation, Peking University Shenzhen Hospital, Shenzhen 518036, China.

Acta biomaterialia
|November 29, 2025
PubMed
概括

这项研究引入了一种新的纳米粒子系统,可以提供反应性氧物种清理器和基因沉默RNA,以对抗骨关节炎. 双重作用的方法有效地减少炎症,并保护软骨免受退化.

关键词:
矩阵金属蛋白酶是一种金属蛋白酶.骨关节炎是一种骨关节炎.聚合物纳米粒子 聚合物纳米粒子有反应性氧物种的反应性氧物种.小干扰RNA是什么?小干扰RNA是什么

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