进行皮肤冠状动脉干预的糖尿病患者的血管内石:来自BENELUX注册表的长期结果
Akshay A S Phagu1, Martijn J H van Oort1, Federico Oliveri1
1Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands.
The American journal of cardiology
|November 29, 2025
概括
血管内透症 (IVL) 辅助的皮肤冠状动脉干预 (PCI) 对糖尿病患者是安全的. 虽然早期风险较高,但糖尿病患者的长期结果与非糖尿病患者相比较.
科学领域:
- 心脏病学 心脏病学
- 干预心脏病学 干预心脏病学
- 医疗器械 医疗器械
背景情况:
- 糖尿病 (DM) 与通过皮肤冠状动脉干预 (PCI) 后更糟糕的结果有关.
- 在接受PCI的糖尿病患者中,血管内透症 (IVL) 的有效性需要进一步定义.
- 糖尿病患者经常出现冠状动脉化增加,这给PCI带来了挑战.
研究的目的:
- 评估IVL辅助PCI在患有或没有DM的患者的安全性和有效性.
- 为了比较糖尿病患者和非糖尿病患者之间的主要心血管不良事件 (MACE) 和程序结果.
- 评估IVL在高风险糖尿病人群中的长期性能.
主要方法:
- 分析了BENELUX-IVL注册表,包括574名患者 (193名患有DM,381名没有).
- 在不同组之间比较程序成功,设备成功和PCI后的光度尺寸.
- 主要终点的评估:MACE在1年和2年 (心血管死亡,MI,TVR).
- 二次终点的评估:手术并发症和全因死亡率.
主要成果:
- 在糖尿病和非糖尿病组中,程序和设备的成功率相似.
- 患有DM的患者在PCI后的最小光线直径和面积较小.
- 糖尿病患者的30天MACE较高 (3.1%对0.3%),但1年和2年的MACE和死亡率相似.
- 糖尿病不是死亡率的独立预测因素 (aOR 1.51;p=0.17).
结论:
- 在糖尿病患者中,IVL辅助的PCI证明了安全性和有效性.
- 用IVL辅助PCI治疗的糖尿病患者的长期心血管结果与非糖尿病患者相似.
- 糖尿病患者的早期MACE较高需要仔细规划和跟踪,特别是在1型糖尿病患者中.
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