在清细胞细胞癌中RPA1,RFC1和POLE表达:免疫和临床相关性

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Updated: Jan 9, 2026

The Use of Reverse Phase Protein Arrays RPPA to Explore Protein Expression Variation within Individual Renal Cell Cancers
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The Use of Reverse Phase Protein Arrays RPPA to Explore Protein Expression Variation within Individual Renal Cell Cancers

Published on: January 22, 2013

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Michał Gola1,2, Jacek Kieżun3, Bartłomiej Emil Kraziński3

  • 1Department of Anatomy and Histology, School of Medicine, University of Warmia and Mazury, Olsztyn, Poland; michal.gola@uwm.edu.pl.

Anticancer research
|November 29, 2025
PubMed
概括

DNA复制蛋白RPA1,RFC1和POLE影响清细胞细胞癌 (ccRCC) 的进展和免疫相互作用. 它们的表达水平与炎症,瘤微环境和患者存活率相关,这表明它们有可能作为生物标志物和治疗点.

关键词:
DNA聚合酶epsilon的催化子单元复制和修复DNA的复制和修复.复制蛋白 A1 的复制蛋白 A1清细胞细胞癌是什么?复制因子C子单元1的复制因子1瘤免疫微环境是一个微环境.

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