在年轻成年人中滥用阿片类药物的风险和保护因素与严重暴力犯罪史相关
相关实验视频
Updated: Jan 9, 2026

06:11
A Conflict Model of Reward-seeking Behavior in Male Rats
Published on: February 20, 2019
7.8K
Susan M Snyder1, Robin M Hartinger-Saunders1
1School of Social Work, Georgia State University, Atlanta, GA, USA.
Journal of evidence-based social work (2019)
|November 29, 2025
概括
具有严重青少年犯罪史的年轻人面临更高的阿片类药物滥用风险. 创伤暴露,PTSD和道德脱离显著增加了这些风险,突出了针对性干预的必要性.
科学领域:
- 犯罪学 犯罪学
- 精神病学是一个精神病学.
- 公共卫生 公共卫生
背景情况:
- 年轻成年人表现出高水平的阿片类药物滥用.
- 严重的未成年犯罪者代表了一个特别容易受到阿片类药物滥用的人口群体.
- 了解风险和保护因素对于制定有效的预防和干预策略至关重要.
研究的目的:
- 调查未经研究的阿片类药物滥用风险和保护因素,在有严重暴力少年犯罪史的年轻成年人中.
- 为这个高风险人群制定预防和干预策略.
主要方法:
- 利用了从路径到拒绝前性研究的数据.
- 包括来自亚利桑那州城 (n=549) 和宾夕法尼亚州费城 (n=483) 的参与者.
- 采用双变量分析和多重后勤回归来评估阿片类药物滥用的预测因素,包括暴力暴露,PTSD,母亲的温暖,道德脱离和人口统计.
主要成果:
- 暴力暴露/受害,PTSD诊断,道德脱离,以及认定为白人或西班牙裔与滥用阿片类药物的可能性增加有关.
- 母亲的温暖没有证明对片滥用有保护作用.
- 重要的预测因素包括PTSD (OR=4.18,p=.039) 和道德脱离 (OR=8.11,p=.000).
结论:
- 创伤,特别是创伤后应激障碍 (PTSD),是该人口中阿片类药物滥用的重要预测因素.
- 调查结果强调了创伤知情护理在解决严重青少年犯罪者中片滥用的关键作用.
- 需要进一步的研究来探索其他研究不足的因素.
相关概念视频
Drug Abuse and Addiction: Pharmacological Phenomena
1.1K
Drug dependence, abuse, and addiction are complex phenomena that can precipitate various abnormal states. Physical dependence refers to a state of pharmacological adaptation to a drug. This adaptation often results in tolerance—a reduced response to the drug after repeated administrations. When the drug use is abruptly stopped, withdrawal symptoms occur due to the body's need to readjust from the pharmacologically induced imbalance. However, tolerance and withdrawal symptoms do not...
1.1K
Opioid Analgesics: Synthetic and Semisynthetic Opioids
888
Synthetic and semisynthetic opioids are pivotal in pain management and tackling opioid addiction. Semisynthetic opioids, including morphinans (morphine derivatives), oxycodone, oxymorphone, hydrocodone, and hydromorphone, have improved pharmacokinetic profiles compared to morphine. Additionally, heroin and 6-MAM (6-Monoacetylmorphine) show better CNS penetration than morphine due to heightened lipid solubility. Hydromorphone, a potent opioid, undergoes hepatic metabolism to form the active...
888
Opioid Analgesics: Morphine and Other Natural Cogeners
813
Opioids are a class of drugs that mimic endogenous opioid peptides and act on opioid receptors, and help in pain relief. These compounds are classified as natural, synthetic, or semi-synthetic. Natural opioids, like morphine, codeine, and thebaine, are derived from the opium poppy plant (Papaver somniferum or Papaver album) and are termed opiates. Synthetic opioids are artificial, while semi-synthetic opioids combine natural and synthetic compounds. Morphine, a prototypical opioid, possesses a...
813
Analgesia and Pain Management
1.4K
Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...
1.4K
Opioid Receptors: Overview
3.9K
Opioid receptors, including the mu (μ, MOR), delta (δ, DOR), and kappa (κ, KOR) types, belong to the rhodopsin family of G protein-coupled receptors. These receptors are located throughout the central and peripheral nervous systems and in non-neuronal tissues such as macrophages and astrocytes. Opioid receptor ligands can be categorized into agonists or antagonists. Highly selective agonists include [d-Ala2, MePhe4, Gly(ol)5]-enkephalin or DAMGO for MOR, [D-Pen2,...
3.9K
Substance Use Disorders Affecting Sleep
369
Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
Understanding the concepts of physical dependence,...
Understanding the concepts of physical dependence,...
369

