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Updated: Jan 9, 2026

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鱼可变新抗原受体对可溶性TNF-α的选择性对抗的结构基础

Obinna C Ubah1, Eric W Lake2, Kendahl L Ott2,3

  • 1Elasmogen Ltd., Aberdeen, UK. obinna.ubah@elasmogen.com.

Nature communications
|November 29, 2025
PubMed
概括

新的抗瘤亡因子α (TNF-α) 变性新抗原受体 (VNAR) 提供了一个更安全的替代方案. 与目前的疗法不同,这些VNAR避免诱导免疫抑制逆信号,可能有利于高风险患者.

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