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眼科临床试验中的种族差异:参与障碍和潜在解决方案

Kerollos Kamel¹, Amy J Yu¹, Alison Y Choi¹

¹University of Pittsburgh, School of Medicine, Pittsburgh, PA, USA.

Eye (London, England)

|November 29, 2025

概括

种族少数群体面临参与眼科临床试验的障碍,尽管眼睛等疾病的疾病负担更高. 解决这些障碍对于公平的医学进步至关重要.

科学领域:

眼科医生眼科眼科
健康差异在健康上的差异
临床试验多样性临床试验多样性

背景情况:

卫生差异仍然存在,边缘化种族群体的医疗保健机会减少,在研究中代表性不足.
眼科在少数群体中发现了像开角玻璃眼和糖尿病黄斑等疾病的不成比例的影响.
在临床试验中代表人数不足可能会阻碍这些群体的医学知识和治疗开发.

研究的目的:

为种族少数群体提供眼科临床试验参与障碍的全面概述.
识别与制度,文化,语言,意识,结构和偏见相关的障碍.
促进公平的代表性,并确保所有种族和民族群体从研究中受益.

主要方法:

这篇叙事综述综合了当前关于临床试验参与障碍的文献.
确定的障碍包括机构,文化,语言,公众意识,结构和研究人员/医生偏见.

主要成果:

许多障碍阻碍了少数种族参与眼科临床试验.
这些障碍跨越了系统,文化和个人层面的因素.

结论:

解决已确定的障碍对于改善临床试验多样性至关重要.
公平的代表性将加速所有人群的医学进步.

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