前列腺中的雌激素调节是良性前列腺增生症男性的种族差异的基础

Teresa T Liu1,2, Laura E Pascal3,4, Emily A Ricke2

  • 1Wegmans School of Pharmacy, St. John Fisher University, Rochester, NY, USA.

The Journal of pathology
|November 30, 2025
PubMed
概括

雌激素受体 (ER) 和类固醇代谢基因表达的种族差异与老年男性的良性前列腺激增症 (BPH) 和下泌尿道症状 (LUTS) 有关. 了解这些途径可能会导致针对LUTS/BPH的向治疗.

相关概念视频

Disorders of the Male Reproductive System01:20

Disorders of the Male Reproductive System

Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
3.9K
Testosterone: Functions and Regulation01:26

Testosterone: Functions and Regulation

The intricate hormonal interplay essential for male reproductive health begins with the release of gonadotropin-releasing hormone (GnRH) by the hypothalamus. This hormone prompts the pituitary gland to secrete follicle-stimulating hormone (FSH) and luteinizing hormone (LH). LH targets the Leydig cells in the testes, stimulating them to produce and release testosterone. In concert with testosterone, FSH acts on the Sertoli cells within the seminiferous tubules to facilitate the release of...
2.0K
Hormonal Regulation01:40

Hormonal Regulation

Hormones regulate a significant portion of digestion through activation of the neuroendocrine system. The neuroendocrine system of digestion contains many different hormones all with multiple functions that are both, directly and indirectly, involved in digestion.
47.7K