评估运动引起的氧化应激的最佳时间:系统性审查和元分析
Chrysovalantis Stachteas1, Nikolaos Georgogiannis1, George G Nastos1
1Department of Physical Education and Sports Science at Serres, Aristotle University of Thessaloniki, Serres, Greece.
Experimental physiology
|November 30, 2025
概括
评估运动诱导的氧化应激的最佳时间因运动类型而异. 非肌肉损伤的运动显示早期的氧化还原生物标志物变化,而肌肉损伤的运动在48-72小时内延迟了峰值.
科学领域:
- 运动生理学 运动生理学
- 生物化学 生物化学
- 氧化压力研究研究 氧化压力研究
背景情况:
- 缺乏关于评估氧化还原生物标志物的最佳时间的共识,阻碍了方法的标准化.
- 了解运动,氧化应激和生理反应之间的时间关系至关重要.
研究的目的:
- 为了确定三个关键的氧化还原生物标志物的最佳运动后评估时间:谷氨,F2-异oprostanes 和蛋白质碳基.
- 为运动诱导氧化应激研究的方法一致性提供基于证据的建议.
主要方法:
- 对103项研究 (n=1418) 的系统综述和元分析,研究了运动后的氧化还原生物标志物.
- 使用随机效应模型计算标准化平均差异.
- 偏差风险的评估 (RoB2,ROBINS-I) 和出版偏差 (埃格尔的测试,漏斗图).
主要成果:
- 谷氨水平在运动后的48小时内立即下降.
- 在运动后的2小时内,F2-异プロ斯坦的摄入量立即增加到2小时.
- 蛋白质碳基因在所有时间点都增加,在48-72小时达到峰值.
- 不损伤肌肉的运动引起了早期反应 (2小时内),而损伤肌肉的运动显示出延迟的峰值 (48-72小时).
结论:
- 氧化还原生物标志物评估的最佳时间取决于炼类型.
- 在几个小时内观察到非肌肉损伤的运动反应,而肌肉损伤的协议会导致延迟的峰值.
- 结果支持方法一致性,有助于研究设计,并将氧化还原生物学与生理结果联系起来.
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