状细胞病患者的社会人口特征和临床特征
Gauri Datt Joshi1, Sher Bahadur Kamar2, Pradip Mishra3
1Department of Social development, Seti Provincial Hospital, Dhangahdi, Kailali, Nepal.
Journal of Nepal Health Research Council
|November 30, 2025
概括
状细胞病 (SCD) 不成比例地影响着尼泊尔的萨鲁社区. 这项研究强调了疼痛和发烧等常见症状,强调了有针对性的公共卫生干预措施的必要性.
科学领域:
- 血液学 血液学 血液学
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 状细胞病 (SCD) 是尼泊尔的一个主要的健康问题,特别影响中西部和Sudurpaschim地区的Tharu人口.
- 这项研究的重点是了解SCD患者在Sudurpashchim省的社会人口形状和临床表现.
研究的目的:
- 调查状细胞病患者的社会人口特征.
- 在研究人群中确定SCD的流行症状和全身表现.
- 为尼泊尔SCD管理的公共卫生战略提供信息.
主要方法:
- 在尼泊尔Sudurpashchim省Seti省医院的健康营期间进行了一项横截面研究.
- 从119名SCD患者中收集了人口统计,流行病学和临床资料的数据,使用结构化问卷.
- 获得了道德认可,并根据预定义的纳入和排除标准将患者纳入.
主要成果:
- 该研究包括119名患者,平均年龄为22.58岁;58.8%是女性.
- 大多数患者 (45.37%) 来自上层低社会经济阶层.
- 常见的症状包括肌肉骨疼痛,虚弱和发烧 (30.5%),其次是黄和胸痛 (21.84%). 其他报告的症状包括呼吸困难,低血红蛋白,贫血和头.
结论:
- 状细胞病影响的是苏杜尔帕什辛省的年轻人,在凯拉利和坎普尔地区的萨鲁社区的患病率更高.
- 关键的系统表现包括疼痛危机,溶血危机,急性胸部综合征,肝病症和部无血管缩.
- 尼泊尔政府迫切需要在现有卫生系统内实施针对性SCD治疗和疼痛管理政策,以减少受影响社区的疾病负担.
相关概念视频
Multiple Allele Traits
37.9K
The Concept of Multiple Allelism
37.9K
Chronic Kidney Disease II: Clinical Manifestations
529
Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...
529
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation
326
Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
326
Factors Affecting Protein-Drug Binding: Patient-Related Factors
283
Protein-drug binding, a pivotal aspect of pharmacokinetics, is subject to considerable variability influenced by an array of patient-related factors. The intricate interplay of age, individual differences, and pathological conditions significantly impact the binding dynamics and subsequent pharmacological effects.
Age stands as a key determinant in protein-drug binding. Neonates, characterized by low albumin content, experience heightened concentrations of unbound drugs such as phenytoin and...
Age stands as a key determinant in protein-drug binding. Neonates, characterized by low albumin content, experience heightened concentrations of unbound drugs such as phenytoin and...
283
Factors Affecting Illness
5.0K
When a person's physical, emotional, intellectual, social development or spiritual functioning is compromised, this deviation from a healthy normal state is called illness. Illness creates stress that in turn harms individuals. Irritation, anger, denial, hopelessness, and fear are behavioral and emotional changes an individual experiences in the phases of illness. A variety of factors influence a person's health and well-being.
For instance, risk factors are connected to illness,...
For instance, risk factors are connected to illness,...
5.0K
Pedigree Analysis
88.7K
Overview
88.7K


