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优化了超偏磁性 Zn_xMn_1-xFe₂O₄ 性磁粘弹性流体的诱导加热,用于高温应用

Mohd Aamir Khan^1,2, Bandla Siva Rama Koteswara Rao^1,2, Mihir Ranjan Padhan^2,3

¹Indian Reference Materials Division (BND), CSIR-National Physical Laboratory, Dr. K. S. Krishnan Marg, New Delhi 110012, India.

ACS applied bio materials

|November 30, 2025

概括

PEG-400涂层的ZnMnFe2O4纳米颗粒显示出对磁流体高温的有希望. 这些生物相容的纳米粒子表现出高效的加热,与临床标准相比,由于优化的磁场和频率.

科学领域:

材料科学材料科学材料科学
纳米技术纳米技术
生物医学工程生物医学工程

背景情况:

超偏磁铁氧化物纳米粒子被探索用于生物医学应用.
磁流体高温症 (MFH) 需要高效和稳定的磁载体.
控制纳米粒子特性对于优化MFH有效性至关重要.

研究的目的:

为了合成和描述PEG-400涂层的Zn_xMn_1-xFe₂O₄纳米粒子.
为MFH应用研究它们的静态和动态磁性特性.
评估它们的加热效率和生物相容性.

主要方法:

合成不同含量的 Zn_xMn_1-xFe₂O₄纳米粒子.
用聚乙烯糖醇 (PEG-400) 进行表面功能化.
使用X射线衍射,泽塔电位测量和交流感应加热试验进行表征.
使用HeLa细胞系进行生物相容性评估.

主要成果:

对于纳米粒子 (11.2-15.4 nm) 证实了单相旋结构.
PEG-400涂层增强了体稳定性 (泽塔电位:-40至-26mV).
达到18.3 kA/m和154.8 kHz的最佳加热 (特定吸收率:273.4 W/g,ILP:5.271 nHm/kg).
非线性放松过程增强了在更高频率的加热.
观察到良好的生物相容性 (70-95%的细胞活力).

结论:

PEG-400涂层的Zn_xMn_1-xFe₂O₄纳米颗粒适用于MFH.
它们的加热效率与临床上已批准的剂量相当.
这些纳米颗粒显示出良好的生物相容性和体稳定性.

关键词:

生物相容性生物相容性感应式加热感应式加热磁热过热是一种磁性过热.磁性纳米流体磁性纳米流体特定的吸收率是什么表面功能化的功能化.

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