开发新的[b]二氧化硫-2-碳胺衍生物作为先进的糖化终产品受体 (RAGE) 对手

Lisa Bonin1,2,3, Matthieu Hedouin2, Christophe Furman3

  • 1Junia, Health and Environment, Laboratory of Sustainable Chemistry and Health, F-59000, Lille, France.

ChemMedChem
|November 30, 2025
PubMed
概括

研究人员开发了新型的[b]二甲胺基衍生物,向高级糖化最终产品 (RAGE) 的受体. 这些化合物显示出对抗炎症和相关疾病的潜力,其中一个模拟物显示出与Azeliragon相似的RAGE相互作用.

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