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暴力和精神病的长期时间相关性:基于EEG的研究

Nina Bang¹, Merete Berg Nesset², Kirsten Rasmussen³

¹St.Olavs Hospital, Centre for Research and Education in Forensic Psychiatry Security, Trondheim, Norway; Department of Mental Health, Norwegian University of Science and Technology (NTNU), Trondheim, Norway; Department of Neuropsychology, Helgeland Hospital, Mosjøen, Norway.

Journal of psychiatric research

|November 30, 2025

概括

在脑电图 (EEG) 中的长距离时间相关性 (LRTC) 在精神病患者中减少,但没有预测暴力风险. 这些神经动态可能不能作为精神病中暴力倾向的可靠标记.

科学领域:

神经科学是一个神经科学.
精神病学是一个精神病学.
生物医学工程生物医学工程

背景情况:

一部分患有精神病的个体表现出较高的暴力风险.
神经动力学,特别是电脑电图 (EEG) 中的长距离时间相关性 (LRTC) 与精神病中的暴力风险之间的关系尚不清楚.

研究的目的:

调查休息状态EEG中的LRTC是否根据暴力史区分患有精神病的个体.
探索LRTC与精神病症状严重程度之间的关联.

主要方法:

休息状态EEG数据从健康对照组 (HC) 收集,从有暴力史的精神病患者 (暴力-PSY) 收集,从没有暴力史的精神病患者 (非暴力-PSY) 收集,从没有精神病的暴力患者 (非暴力-PSY) 收集.
在闭眼和开眼条件下,LRTC在alpha和beta频段使用detrended波动分析 (DFA) 来量化.
八个LRTC指标是从两种频段和条件的平均和峰值幅度得出的.

主要成果:

眼睛开放状态LRTC在不同组之间没有显著差异.
与HC相比,非暴力PSY组的闭眼条件显著降低了LRTC,对于α和β平均/峰值幅度,与HC相比.
在暴力PSY和非暴力PSY组之间没有发现LRTC的显著差异.
较低的α频段LRTC与症状严重程度的增加相关,包括总PANSS和抑郁分数.

结论:

与对照组相比,在非暴力精神病患者中观察到闭眼条件下减少LRTC.
LRTC没有区分精神病患者有或没有暴力史.
目前的发现为LRTC作为精神病中的暴力风险预测器提供了有限的证据.

关键词:

这是一个EEGEEGEEGEEGEEGEEGEEG.长距离时间相关性 (LRTC)精神分裂症是一种精神分裂症.暴力暴力暴力暴力

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