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对CAR-scFv链接器变体的计算设计,用于增强对B细胞恶性瘤的CD20结合

Purva Khodke1, Bajarang Vasant Kumbhar1

  • 1Department of Biological Sciences, Sunandan Divatia School of Science, SVKM's Narsee Monjee Institute of Management Studies (NMIMS) Deemed-to-be University, Vile Parle (West), Mumbai 400056, Maharashtra, India.

Computers in biology and medicine
|November 30, 2025
PubMed
概括

惠特洛链接器通过提高结合亲和力和稳定性来增强抗CD20化学抗原受体 (CAR) -T细胞疗法. 这种分子建模方法为下一代CAR结构提供了一个有希望的策略,该结构针对B细胞恶性瘤中的CD20.

关键词:
在CAR-T细胞疗法中.CD20 CD20 是一个CD20 CD20 是一个CD20.G(4)S(3) 的链接器.脂质双层膜是什么意思这就是Ofatumumabumab.塔楼的表观就是塔楼的表观.惠特洛的左边运动员

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