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单细胞转录组分析揭示了老化过程中内皮细胞的分子变化

Yongle Sun1, Yini Dai1, Yehu Yin1

  • 1Institute of Medicine, Jishou University, Jishou, Hunan 416000, China.

Archives of gerontology and geriatrics
|November 30, 2025
PubMed
概括

血管衰老是心血管疾病的原因之一,涉及到内皮细胞中的分子变化. 这项研究揭示了关键的基因表达转移和像AP-1这样的转录因子,这表明衰老的结果是功能性基因损失.

关键词:
AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1年龄化 衰老 衰老在Egr1Egr1Egr1内皮细胞是内皮细胞.单细胞转录组是一个单细胞转录组.

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