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循环氧基因酶-2 抑制改善高胆固醇血引起的心脏功能障碍

Bernadett Kiss1, Regina N Nagy1, Gábor B Brenner1

  • 1Department of Pharmacology and Pharmacotherapy, Semmelweis University, Nagyvárad tér 4, Budapest H-1089, Hungary; Center for Pharmacology and Drug Research & Development, Semmelweis University, Nagyvárad tér 4, Budapest H-1089, Hungary.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
|November 30, 2025
PubMed
概括

罗菲科克西布在老鼠中惊人地改善了高胆固醇血引起的心脏功能障碍. 这项研究揭示了rofecoxib的存在.

关键词:
环氧化原酶-2 抑制剂隐藏的心脏毒性 隐藏的心脏毒性超高胆固醇血症是什么情况肌肉心脏再注射损伤的损伤临床前药物安全研究

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