相关实验视频

Updated: Jan 9, 2026

In vitro Modeling for Neurological Diseases using Direct Conversion from Fibroblasts to Neuronal Progenitor Cells and Differentiation into Astrocytes
11:42

In vitro Modeling for Neurological Diseases using Direct Conversion from Fibroblasts to Neuronal Progenitor Cells and Differentiation into Astrocytes

Published on: June 10, 2021

5.4K

直接诱导神经元在神经退行性疾病建模中的应用

Keita Matsumoto1, Sumihiro Maeda2

  • 1Department of Physiology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-858, Japan.

Neuroscience research
|November 30, 2025
PubMed
概括

从人体细胞中直接诱导的神经元 (iN) 为研究神经退行性疾病提供了强大的工具. 这种方法绕过了早期的细胞发育阶段,保留了与年龄相关的关键患者信息,以便更好地模拟疾病和个性化医学.

关键词:
阿尔茨海默氏症的疾病是阿尔茨海默氏症.直接转换的神经元的神经元.这里是 INs INs.神经退行性疾病的神经退行性疾病塔乌·塔乌 (Tau Tau) 是一个

更多相关视频

Generation of Human Neurons and Oligodendrocytes from Pluripotent Stem Cells for Modeling Neuron-Oligodendrocyte Interactions10:53

Generation of Human Neurons and Oligodendrocytes from Pluripotent Stem Cells for Modeling Neuron-Oligodendrocyte Interactions

Published on: November 9, 2020

5.4K
Simple Generation of a High Yield Culture of Induced Neurons from Human Adult Skin Fibroblasts09:07

Simple Generation of a High Yield Culture of Induced Neurons from Human Adult Skin Fibroblasts

Published on: February 5, 2018

10.8K

相关概念视频

EPS and iPS Cells in Disease Research01:21

EPS and iPS Cells in Disease Research

Embryonic and induced pluripotent stem cells are excellent models for disease research because of their ability to self-renew and differentiate into most cell types. Somatic cells from a patient are isolated and reprogrammed into induced pluripotent stem cells or iPSCs. These iPSCs are later differentiated into the desired cell type, which mirrors the diseased cell of the patient. In this way, disease models have been created for investigating diseases such as Down syndrome, type I diabetes,...
3.3K