COVID-19对AMR的影响:快速范围审查,公平分析和证据差距地图研究
Fiona Emdin1, Ebiowei Samuel F Orubu2, Susan Rogers Van Katwyk2
1York University, Toronto, Ontario, Canada fiona.emdin@globalstrategylab.org.
BMJ global health
|November 30, 2025
概括
COVID-19大流行对抗菌素耐药性 (AMR) 产生了多种影响. 虽然在医院中增加的抗微生物药物的使用加剧了AMR,但社区的感染控制措施可能已经减少了AMR,这凸显了在未来的健康危机中需要综合战略.
科学领域:
- 公共卫生 公共卫生
- 传染性疾病 传染性疾病
- 卫生系统研究 卫生系统研究
背景情况:
- COVID-19大流行可能改变了抗菌素耐药性 (AMR) 的驱动因素.
- 现有的健康不平等可能被大流行对AMR的影响加剧了.
- 了解这些影响对于未来的流行病准备至关重要.
研究的目的:
- 审查COVID-19如何影响抗微生物使用,感染预防和控制 (IPC) 以及卫生系统使用.
- 评估这些医疗保健系统因素对抗菌素耐药性的影响.
- 在疫情期间确定与AMR相关的研究差距和公平性考虑.
主要方法:
- 对同行评审文献和世卫组织COVID-19数据库的快速范围审查.
- 在MEDLINE,Embase和Cochrane数据库中进行的搜索.
- 数据提取的重点是AMR的出现,传播和数量,并评估了公平性和证据质量.
主要成果:
- 在COVID-19期间增加抗微生物药物的使用与医院的AMR更高相关.
- 针对COVID-19的IPC措施可能会降低社区获得的AMR.
- 关于卫生系统使用变化及其对抗药物耐药性的影响,存在重大知识差距;很少有研究涉及公平.
结论:
- COVID-19对AMR的影响是复杂的,并且取决于背景.
- 需要对卫生系统和影响大流行期间AMR的社会经济因素进行更严格的研究.
- 整合抗菌管理,IPC和以公平为重点的监测对于未来的流行病准备至关重要.
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