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氨基酸补充剂加速了运动诱导的细胞透到人类骨肌肉中的解决

Mengxin Ye^1,2, Giancarlo Condello³, Kuo-Ching Chao⁴

¹College of Physical Education and Health Sciences, Zhejiang Normal University, Jinhua, People's Republic of China.

Journal of the International Society of Sports Nutrition

|November 30, 2025

概括

氨基酸补充会加速运动肌肉中的炎症解消. 骨髓衍生细胞为肌肉修复贡献线粒体,增强抵抗运动后的恢复.

科学领域:

运动生理学和运动营养.
细胞生物学和肌肉再生.
免疫学和炎症研究.

背景情况:

已知氨基酸可以激活中性粒细胞的功能,如细胞分裂和自由基释放in vitro.
抵抗运动会诱导骨肌中的炎症反应,其特征是髓氧化酶阳性 (MPO+) 细胞的透.

研究的目的:

研究氨基酸补充对运动后人类骨肌肉中MPO+细胞积累的影响.
探索透细胞在线粒体内容变化和运动和补充剂后细胞衰老中的作用.

主要方法:

一项随机,双盲,安慰剂控制的交叉研究,涉及十名年轻男子.
在基线时进行抵抗运动,然后进行肌肉活检,在运动后立即 (0小时),以及在运动后24小时.
对MPO+细胞透,8-基-2-脱氧氨酸 (8-OHdG) 水平,线粒体密度和p16Ink4a mRNA表达的分析.

主要成果:

24小时后,抵抗运动增加了MPO+细胞透和8-OHdG水平.
氨基酸补充加速MPO+细胞透到0小时,水平降低了24小时.
透的细胞,包括MPO阴性细胞,为运动肌肉贡献了线粒体,在24小时恢复期间增加了含量约2倍. 细胞衰老标志物p16Ink4a mRNA在氨基酸治疗后较早减少.

结论:

氨基酸补充剂加快了炼的骨肌肉中炎症的解决.
骨髓衍生细胞有助于快速的线粒体积增多,以应对肌肉损伤,帮助恢复.
这些发现强调了透细胞在运动后的肌肉修复和适应过程中的双重作用.

关键词:

一个MPO,一个MPO.作为一个中性粒细胞.这就是ROSOS ROS.氨基酸是氨基酸中的一种.在体内,线粒体转移在体内发生.

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