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在泰国北部的野地消防员中,系统性炎症,肺功能和呼吸系统症状之间的关联
Singkaew Pannawadee1, Pudpong Punyisa1, Tonchoy Prakasit1
1Department of Occupational Health and Safety, School of Public Health, University of Phayao, Thailand.
野地消防员显示系统性炎症 (hs-CRP) 和肺功能减弱之间的联系,导致更多的呼吸道症状. 监测生物标志物和肺功能对于他们的职业健康至关重要.
科学领域:
- 职业健康 职业健康 职业健康
- 环境医学 环境医学
- 肺部医学 肺部医学
背景情况:
- 野地消防员面临呼吸系统问题和全身炎症的风险.
- 对炎症生物标志物,肺功能和症状的综合评估是有限的,特别是在泰国消防员中.
研究的目的:
- 研究泰国北部野地消防员的炎症生物标志物,肺功能,呼吸系统症状和健康因素之间的关联.
主要方法:
- 用问卷和生理测量对146名野地消防员进行横截面研究.
- 评估了高灵敏度C反应蛋白 (hs-CRP),部分呼出的氧化 (FeNO) 和肺功能 (FVC,FEV1,FEF25-75).
- 统计分析包括曼-惠特尼U,克鲁斯卡尔-瓦利斯和斯皮尔曼的相关性测试.
主要成果:
- 中位数的hs-CRP为1.44μg/l;中位数的FeNO为11.83ppb.
- 在hs-CRP和BMI之间发现了积极的关联,以及hs-CRP和FeNO.
- 肺功能参数与hs-CRP负相关;升高的hs-CRP和降低的肺功能与增加的呼吸系统症状有关.
结论:
- 系统性炎症,肺功能下降和呼吸系统症状在野地消防员中相互联系.
- 强调需要在职业健康监测中对生物标志物和肺功能进行综合监测,以便早期检测.
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