根据年轻糖尿病患者肥胖状况的变化,心血管疾病发病率的差异
Do Kyeong Song1, Yeon-Ah Sung2, Young Sun Hong2
1Department of Internal Medicine, Ewha Womans University School of Medicine, 25 Magokdong-ro 2-gil, Gangseo-gu, Seoul, 07804, Korea. dksong@ewha.ac.kr.
Cardiovascular diabetology. Endocrinology reports
|November 30, 2025
概括
在患有糖尿病的年轻人中,腹部肥胖显著增加了心血管疾病 (CVD) 的风险. 保持非肥胖状态,特别是通过减少腰围,可以降低中风和心力衰竭的风险.
科学领域:
- 心脏病学 心脏病学
- 内分泌学 在内分泌学.
- 公共卫生 公共卫生
背景情况:
- 肥胖和心血管疾病 (CVD) 在年轻发病糖尿病之间的联系尚未得到充分证实.
- 调查心血管疾病发病率和改变腹部肥胖的影响对这一群体至关重要.
研究的目的:
- 为了检查40岁之前被诊断患有糖尿病的成年人心血管疾病的发病率.
- 评估随着时间的推移,腹部肥胖状况的变化如何影响心血管疾病风险.
主要方法:
- 来自韩国国家健康保险服务数据库 (2009-2021) 的糖尿病患者大队列 (93,453名20-39岁的成年人) 的分析.
- 参与者根据腹部肥胖的变化进行分组:持续的非肥胖,过渡到肥胖,过渡到非肥胖和持续的腹部肥胖.
- 考克斯的比例危险模型被用来计算心血管疾病的危险比率 (HRs),并根据各种风险因素进行调整.
主要成果:
- 开始时的腹部肥胖与所有心血管疾病事件的风险增加1.53倍有关.
- 持续的腹部肥胖显示所有心血管疾病 (HR 1.59),冠心病 (HR 1.56),中风 (HR 1.57) 和心力衰竭 (HR 1.69) 的风险更高.
- 与那些保持不肥胖的人相比,减轻腹部肥胖的人没有显著增加出血性中风或心力衰竭的风险.
结论:
- 腹部肥胖是患有糖尿病的年轻成年人心血管疾病的重要危险因素.
- 体重管理,特别是减小腰围,可能会降低特定心血管事件的风险,如出血性中风和心力衰竭.
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