非传染性疾病对低资源环境中的孕产妇和产前期结果的影响
Leevan Tibaijuka1,2,3, Adeline A Boatin4, Yarine Fajardo Tornes5
1Department of Obstetrics and Gynecology, Mbarara Regional Referral Hospital, Mbarara, Uganda. ltibaijuka@must.ac.ug.
Maternal health, neonatology and perinatology
|November 30, 2025
概括
患有非传染性疾病 (NCD) 的孕妇面临两倍严重的孕产妇和产周结局的风险. 早期发现非传染性疾病和适当的产前护理 (ANC) 对于改善低资源环境中的母亲健康至关重要.
科学领域:
- 产科和妇科 产科和妇科
- 公共卫生 公共卫生
- 心脏病学 心脏病学
背景情况:
- 非传染性疾病 (NCD) 对生育年龄的妇女来说是一个越来越大的问题,可能会影响孕产妇和产周健康.
- 关于非传染性疾病对低资源环境中的怀孕结果的影响的数据有限.
研究的目的:
- 调查妊娠前非传染性疾病对严重的孕产妇和不良周产期结局的影响.
- 在乌干达的姆巴拉拉区域推医院 (MRRH) 评估孕妇的这些结果.
主要方法:
- 从2022年7月到2023年10月,对300名孕妇 (100名患有非传染性疾病,200名没有) 进行前性队列研究.
- 数据收集包括基线非传染性疾病,社会人口统计学,以及对严重的孕产妇和产周结局的随访.
- 多变量后勤回归分析了非传染性疾病,产前护理 (ANC) 访问和结果之间的关联,并调整了混因素.
主要成果:
- 患有非传染性疾病的妇女的严重孕产妇结果 (36.0%与22.0%) 和不良周产期结果 (69.0%与44.5%) 的比例显著更高.
- 具体的严重孕产妇结局包括在NCD组中更高的孕产妇死亡率,心力衰竭,ICU入院,肺栓塞和败血症.
- 在非传染性疾病组中,不良周产期结局更为频繁,包括流产,新生儿死亡和NICU入院.
- 怀孕前的非传染性疾病 (aOR: 2.02) 和少于四次ANC访问 (aOR: 2.25) 与严重的孕产妇和产周并发症风险增加有关.
结论:
- 怀孕前的非传染性疾病和不足的ANC显著增加了严重的孕产妇和不良周产期结果的风险.
- 将非传染性疾病管理整合到孕产妇护理中,并确保足够的ANC覆盖率至关重要.
- 需要有针对性的,多学科的干预措施,以减轻在资源有限的环境中这些风险.
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