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解码TP53-突变性急性髓性白血病的分子驱动因素:临床影响和预后见解

Lin-Ya Wang1, Hai-Tao Gao1, Qiang Fu1

  • 1Peking University People's Hospital, Peking University Institute of Hematology, National Clinical Research Center for Hematologic Disease, Beijing Key Laboratory of Cell and Gene Therapy for Hematologic Malignancies, Peking University, Beijing, China.

British journal of haematology
|December 1, 2025
PubMed
概括

分子特征显著影响TP53-突变性急性髓性白血病 (AML) 的预后. 特定的TP53突变部位和RUNX1-RUNX1T1等同时发生的突变会影响患者的治疗结果和治疗反应.

关键词:
这种突变是TP53突变.急性髓性白血病急性骨髓性白血病遗传特征 遗传特征 遗传特征

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