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Updated: Jan 9, 2026

Vasodilation of Isolated Vessels and the Isolation of the Extracellular Matrix of Tight-skin Mice
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在全身性硬化症中,CCL19+ 纤维细胞-CCR7+ T 细胞交叉协调免疫纤维细胞信号网络

Wei Guo1, Zhaohua Li1, Dan Xu1

  • 1Department of Rheumatology and Immunology, Peking University Third Hospital, Beijing, China.

The British journal of dermatology
|December 1, 2025
PubMed
概括

系统性硬化症 (SSc) 纤维化是由CCL19+纤维细胞驱动的,这些纤维细胞招募CCR7+ T细胞. 阻止这种CCL19-CCR7相互作用在小鼠模型中减少了纤维化,揭示了SSc病变发生的关键途径.

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