与全身和区域麻醉相关的外科外围神经损伤的发生率:一项观察性研究
Tom Luo1, Janneke Berecki-Gisolf2, Stuart Marshall1,3
1Department of Anaesthesia, Peninsula Health, Melbourne, VIC, Australia.
Anaesthesia
|December 1, 2025
概括
在外科手术期间的外围神经损伤很少见,每10万例外科入院病例中发生率为14.6例. 危险因素包括综合麻醉,肥胖和某些手术.
科学领域:
- 麻醉学 麻醉学
- 神经外科 神经外科
- 公共卫生 公共卫生
背景情况:
- 术前外围神经损伤 (PNI) 是罕见的,使得发病率估计和风险因素识别具有挑战性.
- 之前的研究依赖于单一中心数据或小型审查,限制了关于PNI发生的最终结论.
研究的目的:
- 确定外科手术期间外围神经损伤的发生率和风险因素.
- 为了准确的风险评估,利用一个全面的全州医院入院数据集.
主要方法:
- 维多利亚州承认的情节数据集 (2015-2024) 的分析.
- 包括5,451,848个非产妇外科入院.
- 确定796个PNI病例,重点关注407个特定的神经损伤.
主要成果:
- 整体PNI发病率:每10万例外科住院病例中有14.6例 (0.014%).
- 特定PNI发生率:每10万例手术入院中有7.5例 (0.007%).
- 与联合麻醉,肥胖,高查尔森并发症指数以及心血管,肌肉骨或神经系统手术相关的风险增加.
结论:
- 术前PNI的发病率低于此前估计的.
- 随着时间的推移,PNI风险似乎正在下降.
- 行政数据库为PNI等罕见事件提供准确的风险估计.
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