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病例报告:外周胀是爱斯坦-巴尔病毒的一个被忽视的表现

Simran Ohri¹, Iden Amiri¹, Gitanjali M Fleischman²

¹Department of Ophthalmology, University of North Carolina, Chapel Hill, NC, USA.

Case reports in ophthalmology

|December 1, 2025

概括

双边外围水,或霍格兰征兆,是传染性单核病 (IM) 的一个未被认可的早期症状. 在年轻患者中识别这种迹象可以防止误诊,并改善对爱斯坦-巴尔病毒 (EBV) 感染的护理.

科学领域:

传染性疾病传染性疾病
儿科儿科儿科
眼科医生眼科眼科

背景情况:

传染性单核病 (IM),通常是由爱斯坦-巴尔病毒 (EBV) 引起的,经典呈现出发烧,喉炎和淋巴腺病变.
霍格兰氏体征,以双边周围眼球水为特征,是IM的不常见但显著的早期表现.
这种迹象往往被忽视,特别是在儿科和年轻成年人群中,导致诊断挑战.

研究的目的:

为了突出霍格兰征兆和传染性单核病之间的低估的关联.
强调识别Hoagland标志对于及时诊断和管理EBV的重要性.
为了强调需要提高提供者对这一演示的认识.

主要方法:

介绍了两项涉及女性患者 (儿科和年轻成年人) 的案例研究,这些患者初步出现了双边围膜胀和非特异性全身症状.
对临床表现,诊断过程和患者结果的审查.
讨论由于对霍格兰标志不熟悉而导致的诊断延迟和误解.

主要成果:

两位患者最初呈现双边外耳周,IM不是最初的疑似诊断.
诊断延迟发生,包括错误诊断和拒绝EBV测试,归因于提供者对Hoagland标志不熟悉.
这两位患者最终通过血清学检测被诊断出EBV,并通过支持性护理进行管理.

结论:

霍格兰标志是传染性单核病的关键早期指标,需要将其纳入无创双眼胀的差异诊断中.
增加对Hoagland标志的提供者教育可以减轻诊断延迟,防止不必要的治疗,并改善EBV感染患者的护理.
识别这种表现对于区分IM与其他疾病,如轨道细胞炎或过敏反应至关重要.

关键词:

爱斯坦-巴尔病毒病毒.霍格兰岛的标志传染病传染病传染病传染病传染性单核病是一种传染性单核病.腹膜周围的胀

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