来自细胞癌的皮肤转移:一个病例报告
Reem Brashi1, Murooj Alotaibi2, Rehab Fadag3
1Department of Dermatology, First Health cluster, Riyadh, Saudi Arabia.
Case reports in dermatology
|December 1, 2025
概括
皮肤转移,由细胞癌 (RCC) 引起的罕见皮肤病变,通常是晚期疾病的信号. 这一案例凸显了识别这些迹象和使用PAX8等标记物进行诊断的重要性.
科学领域:
- 在瘤学瘤学.
- 皮肤病学 皮肤病学
- 病理学 病理学 病理学
背景情况:
- 细胞癌 (RCC) 的皮肤转移是罕见的.
- 它们往往表明晚期RCC的预后不佳.
- 临床表现和诊断标记尚未得到充分确立.
研究的目的:
- 报告来自RCC的皮肤转移病例.
- 突出诊断方面的挑战和潜在的标记.
- 为了强调认识到这种罕见的呈现的重要性.
主要方法:
- 一个69岁的男性患有第四期RCC的案例研究.
- 皮肤学检查显示皮下结节和紫色病变.
- 活检和免疫组织化学 (IHC) 染色用于诊断确认.
主要成果:
- 皮肤转移性癌瘤通过活检和IHC证实.
- 对于胰岛素,CD10和维丁,IHC资料显示为阳性.
- PAX8染色是负的,表明一个独特的诊断形状.
结论:
- 皮肤转移可能是晚期RCC的不常见表现.
- 在这种情况下,PAX8阴性可能是有用的诊断标记.
- 早期识别对于患者的管理和预后至关重要.
更多相关视频
06:38A Syngeneic Mouse Model of Metastatic Renal Cell Carcinoma for Quantitative and Longitudinal Assessment of Preclinical Therapies
Published on: April 12, 2017
14.1K
07:50Utilization of Ultrasound Guided Tissue-directed Cellular Implantation for the Establishment of Biologically Relevant Metastatic Tumor Xenografts
Published on: May 25, 2018
8.8K
相关概念视频
02:30Metastasis
5.4K
Metastasis is the spread of cancer cells from the original site to distant locations in the body. Cancer cells can spread via blood vessels (hematogenous) as well as lymph vessels in the body.
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...
5.4K
01:30Skin Cancer
5.2K
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
5.2K