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Updated: Jan 9, 2026

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针对MASLD的THR-β:机制和药物开发

Yunlong Hua1, Yang Liu2, Lianjun Xing3

  • 1Institute of Digestive Diseases, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, 200032, People's Republic of China.

Drug design, development and therapy
|December 1, 2025
PubMed
概括

与代谢功能障碍相关的脂肪性肝病 (MASLD) 是常见的,治疗方法很少. 甲状腺激素受体β (THR-β) 激动剂,如Resmetirom,通过向肝脏新陈代谢,对MASLD有希望,但需要进一步研究.

关键词:
激进分子的激进分子.与代谢功能障碍相关的脂肪肝炎.与代谢功能障碍相关的脂肪性肝病.甲状腺激素是甲状腺激素的一种.甲状腺激素受体-β-β的受体.

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