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Updated: Jan 9, 2026

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癌症痕迹:用于驱动和调节基因识别的网络癌症演变的多阶段单细胞分析

Komlan Atitey1, Caitlin E Hughes2, Joseph C Fusco3

  • 1Biostatistics and Computational Biology Branch, National Institute of Environmental Health Sciences (NIEHS), 111 T W Alexander Dr Rall Building, Research Triangle Park, NC 27709, United States.

Computational and structural biotechnology journal
|December 1, 2025
PubMed
概括

癌症跟踪 (CancerTrace) 通过使用时间感知单细胞RNA测序数据,识别患者特定的癌症驱动因素及其调节因素. 这种计算框架揭示了动态的因果关系,推进了精确的瘤学.

关键词:
癌症驱动基因是癌症的驱动基因.基因监管网络是基因监管网络.肺部腺癌瘤是肺部腺癌.非驾驶员的监管机构一个单细胞RNA-seqq.变化的贝叶斯推理推理.

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