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Updated: Jan 9, 2026

Production of Human CRISPR-Engineered CAR-T Cells
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瘤特异性CRISPR导向基因编辑作为固体瘤治疗的组合疗法的功能性特征

Kelly H Banas1, Pawel A Bialk1, Natalia Rivera-Torres1

  • 1Gene Editing Institute, ChristianaCare Health System, Newark, DE 19713, USA.

Molecular therapy. Oncology
|December 1, 2025
PubMed
概括

基因编辑CRISPR可以通过破坏NRF2通路来克服癌症药物耐药性. 即使是瘤细胞中NRF2的部分干扰也能恢复化疗的敏感性,提供了一个有前途的治疗策略.

关键词:
克里斯普尔-Cas9是什么意思MT: 定期发行 定期发行这就是NRF2的NRF2.化学敏感性 化学敏感性药物耐药性 耐药性 药物耐药性基因编辑 基因编辑脂质纳米颗粒的使用方法非小细胞肺癌 (非小细胞肺癌)固体瘤是一种固体瘤.特定于瘤的瘤特异性.

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