使用卡瓦或克拉的临床特征成年人:对日益流行的植物产品的物质使用障碍评估挑战
Katherine Hill1, Edward W Boyer2, Kirsten E Smith3
1Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT, USA.
Drug and alcohol dependence reports
|December 1, 2025
概括
克拉和卡瓦是受欢迎的精神活性植物. 一项研究发现,38.1%的kratom用户符合物质使用障碍标准,同时使用kava会增加这种风险.
科学领域:
- 民族植物学 民族植物学
- 心理药理学 心理药理学
- 公共卫生 公共卫生
背景情况:
- 克拉 (Mitragyna speciosa) 和卡瓦 (Piper methysticum) 是越来越受欢迎的精神活性植物.
- 由于消费率不断上升,了解使用者的临床特征至关重要.
研究的目的:
- 为了描述使用 kratom 和/或 kava 的个体的临床概况.
- 评估物质使用障碍 (SUD) 症状和感知与日常生活的兼容性.
主要方法:
- 美国成年人进行了一项在线调查,报告过去一年使用了kratom或kava.
- 诊断和统计手册-5 (DSM-5) SUD标准被应用来评估过去一年的症状.
- 参与者报告了克拉和卡瓦的感知效应和日常生活的兼容性.
主要成果:
- 在367名参与者中,91.3%的人报告过一生使用kratom,49.0%的人报告过一生使用kava,有显著的重叠 (40.3%).
- 38.1%的使用者满足了过去一年SUD标准;与卡瓦的联合使用与使用超过预期和耐受性的更高率有关.
- 过去一年卡瓦的SUD标准不常见 (7.5%),不论是kratom的同时使用. Kratom 效应通常被认为比 kava 效应更适合日常生活.
结论:
- kratom和kava的同时使用带来了独特的临床挑战,需要对它们的联合作用进行进一步的研究.
- 克拉和卡瓦都可能存在物质使用障碍,需要对患者层面的因素和其他物质使用进行上下文评估.
- 需要对这些植物单独或组合的奖励和强化特性进行系统的研究.
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