在接受机械通风的患者中,与非COVID-19肺炎相关的长期发病率
Alexander T Clark1, Clark I Strunk1, Matthew W Semler1
1Department of Emergency Medicine (A. T. C., C. I. S., S. D., W. H. S., and J. H. H.), Vanderbilt University Medical Center, Tennessee Valley Healthcare System; the Division of Allergy, Pulmonary, and Critical Care Medicine (M. W. S., J. D. C., J. C. J., E. W. E., A. L. K., P. T. B., and A. L.), the Vanderbilt Institute for Clinical and Translational Research (M. W. S., J. D. C., and W. H. S.), Vanderbilt University Medical Center; the Department of Biostatistics (C. A. J., G. W., and R. R.), the Critical Illness, Brain Dysfunction, and Survivorship Center (J. C. J., E. W. E., A. L. K., P. T. B., A. L., and J. H. H.), the Department of Anesthesiology (R. E. F.), Vanderbilt University Medical Center; and the Geriatric Research, Education, and Clinical Center (J. C. J., E. W. E., and J. H. H.), Tennessee Valley Healthcare System, Nashville, TN.
在机械通风中患有非COVID-19肺炎的重症患者在出院一年后经常经历长期的认知和功能障碍,心理困扰和生活质量差. 需要进一步的研究来开发干预措施,以减轻这些不良结果.
科学领域:
- 关键护理医学 关键护理医学
- 肺部病理学 肺部病理学
- 神经学 神经学
背景情况:
- COVID-19大流行强调了急性呼吸道疾病的长期健康后果.
- 然而,非COVID-19肺炎的长期发病率,特别是机械通风患者的长期发病率,仍然不太了解.
研究的目的:
- 为了调查12个月的长期认知障碍 (LTCI) 的负担.
- 评估非COVID-19肺炎需要机械通风的重症患者的功能障碍,心理困扰和生活质量.
主要方法:
- 一项前性队列研究,涉及接受机械通风的非COVID-19肺炎患者.
- 用蒙特利尔盲人认知评估对12个月的认知功能进行了评估.
- 二次结果包括日常生活活动 (ADL),身体功能,心理痛苦 (PTSD,抑郁症,焦虑症) 和生活质量.
主要成果:
- 在96名幸存者中,57.3%患有LTCI,13.5%患有执行功能障碍.
- 超过50%的人有基本或仪器ADL的损伤,44.0%的人有身体残疾.
- 观察到显著的心理困扰,其中17.8%符合PTSD标准,37.8%抑郁,46.7%焦虑.
结论:
- 许多接受机械通风的非COVID-19肺炎幸存者面临长期认知障碍.
- 许多幸存者经历功能缺陷,身体残疾和心理后果,影响他们的生活质量.
- 显然需要采取干预措施来减少这些不利的长期结果.
相关概念视频
Pneumonia I: Introduction
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Pneumonia III: Complications and Assessment
Pneumonia II: Pathophysiology
Pneumonia IV: Management
Bacterial Pneumonia Treatment
For bacterial pneumonia, antibiotics serve as the cornerstone of therapy. Initial treatment often begins with empirical antibiotics, tailored to the anticipated causative organism and adjusted based on culture results. Key antibiotic choices include:
Mechanical Ventilation III: Noninvasive Ventilation
Noninvasive Positive-Pressure Ventilation...
Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:


